Yeah, that would work. Basically when you create your sculptor page, you could set the background image of the different areas from the sliced images.
Once you have your sculptor page, i recommend to create a template from it so you can create the rest of the pages based on that template, so your site is consistent. You could also create a SiteAssist Pro Template.
here is a link that talks a little about templates:
You could also read this PDF on how to create a SiteAssist pro template from a sculptor page:
and click on the How Tos tab.