Jimmy, thank you. My problem was that I didn't update the files back to my local from the server after installing PS3.
Before uploading I right clicked on the PS3 folder and unchecked Read-Only and applied to all folders, subfolders and files.
1. I uploaded the PS3 file via FileZilla to my hosting account and installed a new copy of PS3 to my hosting account.
2. I successfully installed PS3 via the install
3. I then downloaded the PS3 files after being installed from my hosting account back to overwrite over the local files.
4. Opened Dreamweaver CS4 and opened main.dwt and made a change.
5. Saved all and received the pop up box to update all pages which made the changes on all main pages at once.
Thanks again Jimmy.