Do you have these files uploaded to your host? If your database does not allow for remote connections then you will need to install PowerStore on the localhost for the database.
It might be best to get a local dev and mysql server setup to work with, then migrate to the site when done. Here are some links to resources for setting up your web server and defining the site in DW:
Setting up testing server for windows:
Define a dynamic site in DW:
if you are getting a 500 error it means that there are problems with your local webserver. You should take a look at the guides linked to above to help you get a local web server and site setup.