so you want to only allows letters and numbers?
you could use a preg_replace() for that which takes a regular expression
<?php echo(preg_replace("/[^A-Za-z0-9]/", "", $row_NewsRS['NewsTitle'])); ?>
See this thread also:
showthread.php?10349055-Remove-non-standard-characters-from-string
you can convert upper case to lower case using strtolower():
function.strtolower.php