Are you sure you are looking in the location:
c:\Users\Jesse\AppData\Roaming\Adobe\Dreamweaver CS4\en_US\
and not another user folder or version of Dreamweaver configuration folder?
If have renamed the configuration folder and you still get the same error, it suggests that the one you renamed was not the one at:
c:\Users\Jesse\AppData\Roaming\Adobe\Dreamweaver CS4\en_US\
Do you also have Dreamweaver CS3 installed? make sure you are not renamiong the CS3 configuration folder by mistake.