Dreamweaver is a visual stylesheet editor :) You would use that to customize anything after the fact after running Sculptor.
If you haven't touched the CSS, that is what presets are for. If you saved a preset, loading that up will accomplish the same thing since it will contain all your styles. You could then just generate a new page, then swap the css to the newly generated one.
I would definitely recommend using a template if you want multiple pages with the same layout. Then like you said - if you run Sculptor again using your saved preset, you can generate a new page, then just update your template with the new CSS (and any new divs if added).
-justin