Can't save edited them in PS4.5

There is no live view, when I click save after modifying the colours of the theme. a blank page comes up with error message. (using safari)

in the admin/common/properties.php file, try changing:

$GLOBALS['permissions'] = array(

    'dir' => 0777,

    'file' => 0666

);

to:

$GLOBALS['permissions'] = array(

    'dir' => 0755,

    'file' => 0755

);

if you continue to have problems, please post back the text of the error message.

Thanks for the reply.
I made the changes to the code and the problem still exists with trying to edit the theme, there is no change when changing the colour slider in global styles. Once I press save, name the theme and press publish I still get the same blank screen.
See error message in the Safari browser below.
Internal Server Error

The server encountered an internal error or misconfiguration and was unable to complete your request.

Please contact the server administrator, webmaster@brandinggroup.com.au and inform them of the time the error occurred, and anything you might have done that may have caused the error.

More information about this error may be available in the server error log.

Additionally, a 404 Not Found error was encountered while trying to use an ErrorDocument to handle the request.

Apache/2.2.15 (Unix) mod_ssl/2.2.15 OpenSSL/0.9.8e-fips-rhel5 mod_bwlimited/1.4 mod_perl/2.0.4 Perl/v5.8.8 Server at brandinggroup.com.au Port 80

I have created a support ticket so we can look into this issue further.

To view and edit your support ticket, please log into your support history:
supporthistory.php

If anyone else is experiencing this same issue, please append to this thread.

I am getting the same error "The server encountered an internal error or misconfiguration and was unable to complete your request." when trying to save designs. I noticed a few others having the same problem. Has anyone come up with a working solution?

you posted a new thread for this issue here:
showthread.php?t=23555


and report that you fixed the problem by

editing the admin/common/properties.php file and changing:

PHP Code:
$GLOBALS['permissions'] = array(
'dir' => 0777,
'file' => 0666
);


to:

PHP Code:
$GLOBALS['permissions'] = array(
'dir' => 0755,
'file' => 0755
);

the setting the permissions on the webassist/plugins/styler folder and all files under it to 755