Hello....When using Dreamweaver and WebAssist products they rely on PHP/MySQL
PHP - is the programming language
MySQL is the database system
You need to scrap Microsoft Access as thats for ASP programming language etc.
You need to first create a working environment for your project using dreamweaver and what is know as a WAMP stack (if Windows) or MAMP Stack (if Apple Mac)
They are easy to setup, just a little program you can get from the internet for free.
WAMPServer is the most popular
and XXAMP is also popular
Then what you would do is create what is known as a LOCAL HOST using one of the above.
Then in Dreamweaver you would set up a local site
Then you would need to login to PHPMyAdmin (which is the MySQL databased installed by one of the 2 programs above) then create your database in the PHPMyAdmin environment.
Thats the summary - if you want more details then feel free to ask :)