After getting Powerbuilder to work on one site I came to use it on a second site.
I believe I set up all of the connections correctly (Dreamweaver certainly connected to the database). When trying to create a powercms content area I get "Unable to edit your database with the provided user credentials. Please make sure the connection user has write access to this database. (You may need to upload the connection to the server if you have made changes recently) - hey ho, here we go again